Zfp57 mutant ES cell lines directly derived from blastocysts

Zfp57 is a master regulator of genomic imprinting in mouse embryos. To further test its functions, we have derived multiple Zfp57 mutant ES clones directly from mouse blastocysts. Indeed, we found DNA methylation imprint was lost at most examined imprinting control regions in these Zfp57 mutant ES c...

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Dettagli Bibliografici
Autori principali: Ho-Tak Lau, Lizhi Liu, Xiajun Li
Natura: Articolo
Lingua:English
Pubblicazione: Elsevier 2016-03-01
Serie:Stem Cell Research
Accesso online:http://www.sciencedirect.com/science/article/pii/S1873506116000027