O‐GlcNAc Transferase Promotes Compensated Cardiac Function and Protein Kinase A O‐GlcNAcylation During Early and Established Pathological Hypertrophy From Pressure Overload
Background Protein posttranslational modifications by O‐linked β‐N‐acetylglucosamine (O‐GlcNAc) increase with cardiac hypertrophy, yet the functional effects of these changes are incompletely understood. In other organs, O‐GlcNAc promotes adaptation to acute physiological stressors; however, prolong...
| Main Authors: | , , , , |
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| 格式: | Article |
| 語言: | English |
| 出版: |
Wiley
2019-06-01
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| 叢編: | Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease |
| 主題: | |
| 在線閱讀: | https://www.ahajournals.org/doi/10.1161/JAHA.118.011260 |