Low dose influenza virus challenge in the ferret leads to increased virus shedding and greater sensitivity to oseltamivir.

Ferrets are widely used to study human influenza virus infection. Their airway physiology and cell receptor distribution makes them ideal for the analysis of pathogenesis and virus transmission, and for testing the efficacy of anti-influenza interventions and vaccines. The 2009 pandemic influenza vi...

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Bibliographic Details
Main Authors: Anthony C Marriott, Brian K Dove, Catherine J Whittaker, Christine Bruce, Kathryn A Ryan, Thomas J Bean, Emma Rayner, Geoff Pearson, Irene Taylor, Stuart Dowall, Jenna Plank, Edmund Newman, Wendy S Barclay, Nigel J Dimmock, Andrew J Easton, Bassam Hallis, Nigel J Silman, Miles W Carroll
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-01-01
Series:PLoS ONE
Online Access:https://journals.plos.org/plosone/article/file?id=10.1371/journal.pone.0094090&type=printable