Longevity interventions modulate mechanotransduction and extracellular matrix homeostasis in C. elegans

Longevity interventions modulate mechanotransduction and extracellular matrix homeostasis in C. elegans

Abstract Dysfunctional extracellular matrices (ECM) contribute to aging and disease. Repairing dysfunctional ECM could potentially prevent age-related pathologies. Interventions promoting longevity also impact ECM gene expression. However, the role of ECM composition changes in healthy aging remains...

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Bibliographic Details
Main Authors: Alina C. Teuscher, Cyril Statzer, Anita Goyala, Seraina A. Domenig, Ingmar Schoen, Max Hess, Alexander M. Hofer, Andrea Fossati, Viola Vogel, Orcun Goksel, Ruedi Aebersold, Collin Y. Ewald
Format: Article
Language:English
Published: Nature Portfolio 2024-01-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-023-44409-2

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https://doi.org/10.1038/s41467-023-44409-2

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