Longevity interventions modulate mechanotransduction and extracellular matrix homeostasis in C. elegans

Abstract Dysfunctional extracellular matrices (ECM) contribute to aging and disease. Repairing dysfunctional ECM could potentially prevent age-related pathologies. Interventions promoting longevity also impact ECM gene expression. However, the role of ECM composition changes in healthy aging remains...

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Main Authors: Alina C. Teuscher, Cyril Statzer, Anita Goyala, Seraina A. Domenig, Ingmar Schoen, Max Hess, Alexander M. Hofer, Andrea Fossati, Viola Vogel, Orcun Goksel, Ruedi Aebersold, Collin Y. Ewald
פורמט: Article
שפה:English
יצא לאור: Nature Portfolio 2024-01-01
סדרה:Nature Communications
גישה מקוונת:https://doi.org/10.1038/s41467-023-44409-2