Epithelial-myeloid exchange of MHC class II constrains immunity and microbiota composition

Epithelial-myeloid exchange of MHC class II constrains immunity and microbiota composition

Summary: Intestinal epithelial cells (IECs) have long been understood to express high levels of major histocompatibility complex class II (MHC class II) molecules but are not considered canonical antigen-presenting cells, and the impact of IEC-MHC class II signaling on gut homeostasis remains enigma...

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Váldodahkkit: W. Zac Stephens, Jason L. Kubinak, Arevik Ghazaryan, Kaylyn M. Bauer, Rickesha Bell, Kate Buhrke, Tyson R. Chiaro, Allison M. Weis, William W. Tang, Josh K. Monts, Ray Soto, H. Atakan Ekiz, Ryan M. O’Connell, June L. Round
Materiálatiipa: Artihkal
Giella:English
Almmustuhtton: Elsevier 2021-11-01
Ráidu:Cell Reports
Fáttát:
MHC class II
intestinal epithelia
antigen processing
microbiome
immunity
macrophage
Liŋkkat:http://www.sciencedirect.com/science/article/pii/S2211124721013899

Interneahtta

http://www.sciencedirect.com/science/article/pii/S2211124721013899

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