Validation of a method for pantoprazole and its sulfone metabolite in goat plasma using high performance liquid chromatography

A selective method for the quantitation of pantoprazole and its metabolite in goat plasma was developed and validated. Chloroform was used for drug extraction and separation occurred on a Symmetry C18 column. A combination of sodium phosphate dibasic (0.1 M, pH 7.5) and acetonitrile were used as the...

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Bibliographic Details
Main Authors: Sherry Cox, Lainey Harvill, Sarah Bullock, Joe Smith, Joan Bergman
Format: Article
Language:English
Published: Elsevier 2022-11-01
Series:Journal of Chromatography Open
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S2772391722000093