Loss of transcriptional heterogeneity in aged human muscle stem cells.

Age-related loss of muscle mass and function negatively impacts healthspan and lifespan. Satellite cells function as muscle stem cells in muscle maintenance and regeneration by self-renewal, activation, proliferation and differentiation. These processes are perturbed in aging at the stem cell popula...

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Bibliografiske detaljer
Main Authors: Emilie Barruet, Katharine Striedinger, Pauline Marangoni, Jason H Pomerantz
Format: Article
Sprog:English
Udgivet: Public Library of Science (PLoS) 2023-01-01
Serier:PLoS ONE
Online adgang:https://doi.org/10.1371/journal.pone.0285018