Loss of transcriptional heterogeneity in aged human muscle stem cells.
Age-related loss of muscle mass and function negatively impacts healthspan and lifespan. Satellite cells function as muscle stem cells in muscle maintenance and regeneration by self-renewal, activation, proliferation and differentiation. These processes are perturbed in aging at the stem cell popula...
Main Authors: | , , , |
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Format: | Article |
Sprog: | English |
Udgivet: |
Public Library of Science (PLoS)
2023-01-01
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Serier: | PLoS ONE |
Online adgang: | https://doi.org/10.1371/journal.pone.0285018 |