m6A-dependent glycolysis enhances colorectal cancer progression

m6A-dependent glycolysis enhances colorectal cancer progression

Abstract Background Epigenetic alterations are involved in various aspects of colorectal carcinogenesis. N 6-methyladenosine (m6A) modifications of RNAs are emerging as a new layer of epigenetic regulation. As the most abundant chemical modification of eukaryotic mRNA, m6A is essential for the regul...

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Bibliographic Details
Main Authors: Chaoqin Shen, Baoqin Xuan, Tingting Yan, Yanru Ma, Pingping Xu, Xianglong Tian, Xinyu Zhang, Yingying Cao, Dan Ma, Xiaoqiang Zhu, Youwei Zhang, Jing-Yuan Fang, Haoyan Chen, Jie Hong
Format: Article
Language:English
Published: BMC 2020-04-01
Series:Molecular Cancer
Subjects:
m6A modification
METTL3
Glycolysis
Colorectal cancer
HK2
GLUT1
Online Access:http://link.springer.com/article/10.1186/s12943-020-01190-w

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