Iron chelation improves ineffective erythropoiesis and iron overload in myelodysplastic syndrome mice

Iron chelation improves ineffective erythropoiesis and iron overload in myelodysplastic syndrome mice

Myelodysplastic syndrome (MDS) is a heterogeneous group of bone marrow stem cell disorders characterized by ineffective hematopoiesis and cytopenias, most commonly anemia. Red cell transfusion therapy for anemia in MDS results in iron overload, correlating with reduced overall survival. Whether the...

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書目詳細資料
Main Authors: Wenbin An, Maria Feola, Maayan Levy, Srinivas Aluri, Marc Ruiz-Martinez, Ashwin Sridharan, Eitan Fibach, Xiaofan Zhu, Amit Verma, Yelena Ginzburg
格式: Article
語言:English
出版: eLife Sciences Publications Ltd 2023-12-01
叢編:eLife
主題:
myelodysplastic dyndrome
deferiprone
ineffective erythropoiesis
iron trafficking
在線閱讀:https://elifesciences.org/articles/83103

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https://elifesciences.org/articles/83103

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