In vitro hepatic biotransformation of the algal toxin pectenotoxin-2
We have investigated the in vitro metabolism of pectenotoxin-2 (PTX-2) using primary hepatocytes from Wistar rats in suspension. Purified PTX-2 was rapidly metabolized. Two major and several minor oxidized PTX-2 metabolites were formed, none of which had retention times corresponding to PTX-1, -11,...
| Autores principales: | , , , |
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| Formato: | Artículo |
| Lenguaje: | English |
| Publicado: |
Elsevier
2020-06-01
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| Colección: | Toxicon: X |
| Acceso en línea: | http://www.sciencedirect.com/science/article/pii/S2590171020300096 |