Topical Delivery of Hedgehog Inhibitors: Current Status and Perspectives

Systemic treatment with hedgehog inhibitors (HHis) is available to treat basal cell carcinomas but their utility is limited by adverse effects. Topical delivery methods may reduce adverse effects, but successful topical treatment depends on sufficient skin uptake, biological response, and time in tu...

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Bibliographic Details
Main Authors: Kristian Kåber Pedersen, Maria Helena Høyer-Hansen, Thomas Litman, Merete Hædersdal, Uffe Høgh Olesen
Format: Article
Language:English
Published: MDPI AG 2022-11-01
Series:International Journal of Molecular Sciences
Subjects:
Online Access:https://www.mdpi.com/1422-0067/23/22/14191