IL-17 induces an expanded range of downstream genes in reconstituted human epidermis model.

IL-17 induces an expanded range of downstream genes in reconstituted human epidermis model.

<h4>Background</h4>IL-17 is the defining cytokine of the Th17, Tc17, and γδ T cell populations that plays a critical role in mediating inflammation and autoimmunity. Psoriasis vulgaris is an inflammatory skin disease mediated by Th1 and Th17 cytokines with relevant contributions of IFN-γ...

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Detalhes bibliográficos
Principais autores: Andrea Chiricozzi, Kristine E Nograles, Leanne M Johnson-Huang, Judilyn Fuentes-Duculan, Irma Cardinale, Kathleen M Bonifacio, Nicholas Gulati, Hiroshi Mitsui, Emma Guttman-Yassky, Mayte Suárez-Fariñas, James G Krueger
Formato: Artigo
Idioma:English
Publicado em: Public Library of Science (PLoS) 2014-01-01
coleção:PLoS ONE
Acesso em linha:https://journals.plos.org/plosone/article/file?id=10.1371/journal.pone.0090284&type=printable

Internet

https://journals.plos.org/plosone/article/file?id=10.1371/journal.pone.0090284&type=printable

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