Unraveling Heterogeneity in the Aging Hematopoietic Stem Cell Compartment: An Insight From Single-cell Approaches

Specific cell types and, therefore, organs respond differently during aging. This is also true for the hematopoietic system, where it has been demonstrated that hematopoietic stem cells alter a variety of features, such as their metabolism, and accumulate DNA damage, which can lead to clonal outgrow...

Ausführliche Beschreibung

Bibliographische Detailangaben
Hauptverfasser: Fei Yang, Craig Nourse, G. Vignir Helgason, Kristina Kirschner
Format: Artikel
Sprache:English
Veröffentlicht: Wiley 2023-06-01
Schriftenreihe:HemaSphere
Online Zugang:http://journals.lww.com/10.1097/HS9.0000000000000895