Active H3K27me3 demethylation by KDM6B is required for normal development of bovine preimplantation embryos

The substantial epigenetic remodeling that occurs during early stages of mammalian embryonic development likely contributes to reprogramming the parental genomes from a differentiated to a totipotent state and activation of the embryonic genome. Trimethylation of lysine 27 of histone 3 (H3K27me3) is...

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Bibliografske podrobnosti
Main Authors: Nhi Chung, Yanina S. Bogliotti, Wei Ding, Marcela Vilarino, Kazuki Takahashi, James L. Chitwood, Richard M. Schultz, Pablo J. Ross
Format: Article
Jezik:English
Izdano: Taylor & Francis Group 2017-12-01
Serija:Epigenetics
Teme:
Online dostop:http://dx.doi.org/10.1080/15592294.2017.1403693