Active H3K27me3 demethylation by KDM6B is required for normal development of bovine preimplantation embryos

The substantial epigenetic remodeling that occurs during early stages of mammalian embryonic development likely contributes to reprogramming the parental genomes from a differentiated to a totipotent state and activation of the embryonic genome. Trimethylation of lysine 27 of histone 3 (H3K27me3) is...

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Bibliografiska uppgifter
Huvudupphovsmän: Nhi Chung, Yanina S. Bogliotti, Wei Ding, Marcela Vilarino, Kazuki Takahashi, James L. Chitwood, Richard M. Schultz, Pablo J. Ross
Materialtyp: Artikel
Språk:English
Publicerad: Taylor & Francis Group 2017-12-01
Serie:Epigenetics
Ämnen:
Länkar:http://dx.doi.org/10.1080/15592294.2017.1403693