Active H3K27me3 demethylation by KDM6B is required for normal development of bovine preimplantation embryos

Active H3K27me3 demethylation by KDM6B is required for normal development of bovine preimplantation embryos

The substantial epigenetic remodeling that occurs during early stages of mammalian embryonic development likely contributes to reprogramming the parental genomes from a differentiated to a totipotent state and activation of the embryonic genome. Trimethylation of lysine 27 of histone 3 (H3K27me3) is...

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Detaylı Bibliyografya
Asıl Yazarlar: Nhi Chung, Yanina S. Bogliotti, Wei Ding, Marcela Vilarino, Kazuki Takahashi, James L. Chitwood, Richard M. Schultz, Pablo J. Ross
Materyal Türü: Makale
Dil:English
Baskı/Yayın Bilgisi: Taylor & Francis Group 2017-12-01
Seri Bilgileri:Epigenetics
Konular:
cattle
embryonic genome activation
h3k27me3
histone demethylation
jmjd3
preimplantation development
reprogramming
totipotency
Online Erişim:http://dx.doi.org/10.1080/15592294.2017.1403693

Internet

http://dx.doi.org/10.1080/15592294.2017.1403693

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