Using circulating microbial cell-free DNA to identify persistent Treponema pallidum infection in serofast syphilis patients
Summary: The question of whether serofast status of syphilis patients indicates an ongoing low-grade Treponema pallidum (T. pallidum) infection remains unanswered. To address this, we developed a machine learning model to identify T. pallidum in cell-free DNA (cfDNA) using next-generation sequencing...
| Main Authors: | , , , , , , , , , |
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| Format: | Article |
| Sprog: | English |
| Udgivet: |
Elsevier
2024-04-01
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| Serier: | iScience |
| Fag: | |
| Online adgang: | http://www.sciencedirect.com/science/article/pii/S2589004224006205 |