Using circulating microbial cell-free DNA to identify persistent Treponema pallidum infection in serofast syphilis patients
Summary: The question of whether serofast status of syphilis patients indicates an ongoing low-grade Treponema pallidum (T. pallidum) infection remains unanswered. To address this, we developed a machine learning model to identify T. pallidum in cell-free DNA (cfDNA) using next-generation sequencing...
Main Authors: | , , , , , , , , , |
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格式: | 文件 |
语言: | English |
出版: |
Elsevier
2024-04-01
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丛编: | iScience |
主题: | |
在线阅读: | http://www.sciencedirect.com/science/article/pii/S2589004224006205 |