Pan-cancer analysis identifies protein arginine methyltransferases PRMT1 and PRMT5 and their related signatures as markers associated with prognosis, immune profile, and therapeutic response in lung adenocarcinoma

Purpose: Protein arginine methyltransferases (PRMTs) regulate several signal transduction pathways involved in cancer progression. Recently, it has been reported that PRMTs are closely related to anti-tumor immunity; however, the underlying mechanisms have yet to be studied in lung adenocarcinoma (L...

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Hlavní autoři: Jia Wang, Meng Wu, Jujie Sun, Minxin Chen, Zengfu Zhang, Jinming Yu, Dawei Chen
Médium: Článek
Jazyk:English
Vydáno: Elsevier 2023-12-01
Edice:Heliyon
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On-line přístup:http://www.sciencedirect.com/science/article/pii/S2405844023092964