Retinoic acid and liver X receptor agonist synergistically inhibit HIV infection in CD4+ T cells by up-regulating ABCA1-mediated cholesterol efflux

Retinoic acid and liver X receptor agonist synergistically inhibit HIV infection in CD4+ T cells by up-regulating ABCA1-mediated cholesterol efflux

<p>Abstract</p> <p>Background</p> <p>Retinoic acids regulate the reverse cholesterol transport by inducing the ATP binding cassette transporter A1 (ABCA1) dependent cholesterol efflux in macrophages, neuronal as well as intestine cells. In the present study, we aim to t...

詳細記述

書誌詳細
主要な著者: Jiang Hong, Badralmaa Yunden, Yang Jun, Lempicki Richard, Hazen Allison, Natarajan Ven
フォーマット: 論文
言語:English
出版事項: BMC 2012-07-01
シリーズ:Lipids in Health and Disease
主題:
ABCA1
ATRA
retinoic acid
TO-901317
RAR
RXR
LXR
cholesterol efflux
HIV-1
CD4+ T cells
オンライン･アクセス:http://www.lipidworld.com/content/11/1/69

インターネット

http://www.lipidworld.com/content/11/1/69

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