Selective Effects of Dopamine Depletion and L-DOPA Therapy on Learning-Related Firing Dynamics of Striatal Neurons

Despite evidence that dopamine neurotransmission in the striatum is critical for learning as well as for movement control, little is yet known about how the learning-related dynamics of striatal activity are affected by dopamine depletion, a condition faced in Parkinson's disease. We made local...

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Bibliographic Details
Main Authors: Hernandez, Ledia F., Kubota, Yasuo, Hu, Dan, Howe, Mark William, Lemaire, Nune, Graybiel, Ann M.
Other Authors: Massachusetts Institute of Technology. Department of Brain and Cognitive Sciences
Format: Article
Language:en_US
Published: Frontiers Research Foundation 2013
Online Access:http://hdl.handle.net/1721.1/81325
https://orcid.org/0000-0001-9197-7711
https://orcid.org/0000-0003-2381-0834
https://orcid.org/0000-0002-4326-7720