Regulation of HIF: prolyl hydroxylases.
Hypoxia inducible factor (HIF) is an alpha/beta heterodimeric transcriptional complex that plays a key role in directing cellular responses to hypoxia. Recent studies have defined novel oxygen-sensitive signal pathways that regulate the activity of HIF by post-translational hydroxylation at specific...
Auteurs principaux: | Stolze, I, Mole, D, Ratcliffe, P |
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Format: | Journal article |
Langue: | English |
Publié: |
2006
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