Regulation of HIF: prolyl hydroxylases.
Hypoxia inducible factor (HIF) is an alpha/beta heterodimeric transcriptional complex that plays a key role in directing cellular responses to hypoxia. Recent studies have defined novel oxygen-sensitive signal pathways that regulate the activity of HIF by post-translational hydroxylation at specific...
المؤلفون الرئيسيون: | , , |
---|---|
التنسيق: | Journal article |
اللغة: | English |
منشور في: |
2006
|