Nur77 controls tolerance induction, terminal differentiation, and effector functions in semi-invariant natural killer T cells

Nur77 controls tolerance induction, terminal differentiation, and effector functions in semi-invariant natural killer T cells

<p>Semi-invariant natural killer T (iNKT) cells are self-reactive lymphocytes, yet how this lineage attains self-tolerance remains unknown. iNKT cells constitutively express high levels of <em>Nr4a1</em>-encoded Nur77, a transcription factor that integrates signal strength...

Πλήρης περιγραφή

Λεπτομέρειες βιβλιογραφικής εγγραφής
Κύριοι συγγραφείς:	Kumar, A, Hill, TM, Gordy, LE, Suryadevara, N, Wu, L, Flyak, AI, Bezbradica, JS, Van Kaer, L, Joyce, S
Μορφή:	Journal article
Γλώσσα:	English
Έκδοση:	National Academy of Sciences 2020

Παρόμοια τεκμήρια

Nur77 controls tolerance induction, terminal differentiation, and effector functions in NKT cells
ανά: Kumar, A, κ.ά.
Έκδοση: (2020)

NUR77 has a cell intrinsic role in natural killer T cell development and function
ανά: Kumar, A, κ.ά.
Έκδοση: (2019)

Granulocyte-Macrophage Colony-Stimulating Factor Regulates Effector Differentiation of Invariant Natural Killer T Cells during Thymic Ontogeny
ανά: Bezbradica, J, κ.ά.
Έκδοση: (2006)

Natural killer T cells: an ecological evolutionary developmental biology perspective
ανά: Kumar, A, κ.ά.
Έκδοση: (2017)

IL-15 Regulates Homeostasis and Terminal Maturation of NKT Cells
ανά: Gordy, LE, κ.ά.
Έκδοση: (2011)

Natural Killer T Cells: An Ecological Evolutionary Developmental Biology Perspective
ανά: Amrendra Kumar, κ.ά.
Έκδοση: (2017-12-01)

NF-κB protects NKT cells from tumor necrosis factor receptor 1-induced death
ανά: Kumar, A, κ.ά.
Έκδοση: (2017)

Staying alive! Signal processing by NF-kappa b protects NKT cells from TNFR1-triggered death
ανά: Kumar, A, κ.ά.
Έκδοση: (2018)

Therapeutic Potential of Invariant Natural Killer T Cells in Autoimmunity
ανά: Luc Van Kaer, κ.ά.
Έκδοση: (2018-03-01)

Characterization and Functional Analysis of Mouse Semi-invariant Natural T Cells
ανά: Kumar, A, κ.ά.
Έκδοση: (2017)

Commitment toward the natural T (iNKT) cell lineage occurs at the CD4+8+ stage of thymic ontogeny
ανά: Bezbradica, JS, κ.ά.
Έκδοση: (2005)

Zeb2 regulates differentiation of long-lived effector of invariant natural killer T cells
ανά: Tomonori Iyoda, κ.ά.
Έκδοση: (2023-10-01)

Invariant γδTCR natural killer-like effector T cells in the naked mole-rat
ανά: Guillem Sanchez Sanchez, κ.ά.
Έκδοση: (2024-05-01)

Human natural killer T cells are heterogeneous in their capacity to reprogram their effector functions.
ανά: Karla A Eger, κ.ά.
Έκδοση: (2006-12-01)

Phase separation of Nur77 mediates XS561-induced apoptosis by promoting the formation of Nur77/Bcl-2 condensates
ανά: Xiaohui Chen, κ.ά.
Έκδοση: (2024-03-01)

Nuclear receptor Nur77 regulates immunomechanics of macrophages
ανά: Sanne C. Lith, κ.ά.
Έκδοση: (2024-06-01)

Nur77 protects the bladder urothelium from intracellular bacterial infection
ανά: Christina A. Collins, κ.ά.
Έκδοση: (2024-09-01)

Regulation of Nuclear Receptor Nur77 by miR-124.
ανά: Alexa Tenga, κ.ά.
Έκδοση: (2016-01-01)

Invariant Natural Killer T Cells
ανά: Antonella Cianferoni
Έκδοση: (2013-12-01)

The two faces of invariant natural killer T cells
ανά: Emma L. Walton
Έκδοση: (2015-12-01)

Natural killer T cells accelerate atherogenesis in mice
ανά: Nakai, Y, κ.ά.
Έκδοση: (2004)

Nur77 Mediates Anaphylaxis by Regulating miR-21a
ανά: Hyein Jo, κ.ά.
Έκδοση: (2024-04-01)

Moving nuclear receptor Nur77 to damaged mitochondria for clearance by mitophagy
ανά: Mengjie Hu, κ.ά.
Έκδοση: (2018-05-01)

Characterization and Functional Analysis of Mouse Invariant Natural T (iNKT) Cells
ανά: Bezbradica, J, κ.ά.
Έκδοση: (2006)

Skeletal muscle Nur77 expression enhances oxidative metabolism and substrate utilization[S]
ανά: Lily C. Chao, κ.ά.
Έκδοση: (2012-12-01)

Histone Deacetylase 7 mediates tissue-specific autoimmunity via control of innate effector function in invariant Natural Killer T Cells
ανά: Herbert G Kasler, κ.ά.
Έκδοση: (2018-04-01)

Spectral killers and Poisson bracket invariants
ανά: Seyfaddini, Sobhan
Έκδοση: (2015)

Cutting Edge: The Ontogeny and Function of Va14Ja18 Natural T Lymphocytes Require Signal Processing by Protein Kinase Cθ and NF-κB
ανά: Stanic, AK, κ.ά.
Έκδοση: (2004)

Dexmedetomidine attenuates inflammation and organ injury partially by upregulating Nur77 in sepsis
ανά: Qian Zhang, κ.ά.
Έκδοση: (2023-06-01)

Insights into mucosal-associated invariant T cell biology from studies of invariant natural killer T cells
ανά: Garner, L, κ.ά.
Έκδοση: (2018)

ASK1 mediates Nur77 expression in T-cell receptor mediated thymocyte apoptosis
ανά: Huo, Jianxin, κ.ά.
Έκδοση: (2020)

FOXA3, a Negative Regulator of Nur77 Expression and Activity in Testicular Steroidogenesis
ανά: Hansle Kim, κ.ά.
Έκδοση: (2021-01-01)

ASK1 Mediates Nur77 Expression in T-Cell Receptor Mediated Thymocyte Apoptosis
ανά: Jianxin Huo, κ.ά.
Έκδοση: (2020-03-01)

Knockout of Nur77 Leads to Amino Acid, Lipid, and Glucose Metabolism Disorders in Zebrafish
ανά: Yang Xu, κ.ά.
Έκδοση: (2022-04-01)

Female Nur77-deficient mice show increased susceptibility to diet-induced obesity.
ανά: Sonia Perez-Sieira, κ.ά.
Έκδοση: (2013-01-01)

The Effect of T69E-mimicked Phosphorylation on the Interaction Between Bcl-2 and Nur77
ανά: Qian XU, κ.ά.
Έκδοση: (2022-03-01)

Antitumor Responses of Invariant Natural Killer T Cells
ανά: Jennie B. Altman, κ.ά.
Έκδοση: (2015-01-01)

Invariant natural killer T cells in lung diseases
ανά: Dongjin Jeong, κ.ά.
Έκδοση: (2023-09-01)

Antigen specificity of invariant natural killer T-cells
ανά: Alysia M. Birkholz, κ.ά.
Έκδοση: (2015-12-01)

Nur77 deletion impairs muscle growth during developmental myogenesis and muscle regeneration in mice.
ανά: Omar Cortez-Toledo, κ.ά.
Έκδοση: (2017-01-01)