The effects of a partitioned var gene repertoire of Plasmodium falciparum on antigenic diversity and the acquisition of clinical immunity.

BACKGROUND: The human malaria parasite Plasmodium falciparum exploits antigenic diversity and within-host antigenic variation to evade the host's immune system. Of particular importance are the highly polymorphic var genes that encode the family of cell surface antigens PfEMP1 (Plasmodium falc...

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Номзүйн дэлгэрэнгүй
Үндсэн зохиолчид: Recker, M, Arinaminpathy, N, Buckee, C
Формат: Journal article
Хэл сонгох:English
Хэвлэсэн: BioMed Central 2008