TGFβ1 neutralization displays therapeutic efficacy through both an immunomodulatory and a non-immune tumor-intrinsic mechanism

TGFβ1 neutralization displays therapeutic efficacy through both an immunomodulatory and a non-immune tumor-intrinsic mechanism

Background Transforming growth factor-β (TGFβ) is emerging as a promising target for cancer therapy, given its ability to promote progression of advanced tumors and to suppress anti-tumor immune responses. However, TGFβ also plays multiple roles in normal tissues, particularly during organogenesis,...

書誌詳細
主要な著者:	Canè, S, Van Snick, J, Uyttenhove, C, Pilotte, L, Van den Eynde, BJ
フォーマット:	Journal article
言語:	English
出版事項:	BMJ Publishing Group 2021

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