TGFβ1 neutralization displays therapeutic efficacy through both an immunomodulatory and a non-immune tumor-intrinsic mechanism
Background Transforming growth factor-β (TGFβ) is emerging as a promising target for cancer therapy, given its ability to promote progression of advanced tumors and to suppress anti-tumor immune responses. However, TGFβ also plays multiple roles in normal tissues, particularly during organogenesis,...
| Главные авторы: | , , , , |
|---|---|
| Формат: | Journal article |
| Язык: | English |
| Опубликовано: |
BMJ Publishing Group
2021
|