Melatonin phase advances circadian rhythm.

We studied the effect of acute (1 day) and subacute (7 days) treatment with melatonin (0.5 mg) on the endogenous rhythms of melatonin secretion in 12 healthy male volunteers, using a placebo-controlled, double-blind, cross-over design. Melatonin given at 1700 h for 7 days significantly advanced the...

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Detalhes bibliográficos
Principais autores: Attenburrow, M, Dowling, B, Sargent, P, Sharpley, A, Cowen, P
Formato: Journal article
Idioma:English
Publicado em: 1995