Out of balance: R-loops in human disease

Out of balance: R-loops in human disease

R-loops are cellular structures composed of an RNA/DNA hybrid, which is formed when the RNA hybridises to a complementary DNA strand and a displaced single-stranded DNA. R-loops have been detected in various organisms from bacteria to mammals and play crucial roles in regulating gene expression, DNA...

Podrobná bibliografie
Hlavní autoři:	Groh, M, Gromak, N
Médium:	Journal article
Jazyk:	English
Vydáno:	Public Library of Science 2014

Podobné jednotky

Out of balance: R-loops in human disease.
Autor: Matthias Groh, a další
Vydáno: (2014-09-01)

R-loop immunoprecipitation: a method to detect R-loop interacting factors
Autor: Beghè, C, a další
Vydáno: (2022)

R-loops associated with triplet repeat expansions promote gene silencing in Friedreich ataxia and fragile X syndrome
Autor: Groh, M, a další
Vydáno: (2014)

RNA/DNA hybrid interactome identifies DXH9 as a molecular player in transcriptional termination and R-loop-associated DNA damage
Autor: Cristini, A, a další
Vydáno: (2018)

SOSS-INTAC: a new gatekeeper of genomic integrity at the interface of transcription and R-loops
Autor: Gromak, N
Vydáno: (2023)

RNA/DNA Hybrid Interactome Identifies DXH9 as a Molecular Player in Transcriptional Termination and R-Loop-Associated DNA Damage
Autor: Agnese Cristini, a další
Vydáno: (2018-05-01)

R-loops associated with triplet repeat expansions promote gene silencing in Friedreich ataxia and fragile X syndrome.
Autor: Matthias Groh, a další
Vydáno: (2014-05-01)

The role of R-loops in the pathology of trinucleotide expansion diseases
Autor: Groh, M
Vydáno: (2015)

Hypoxia-induced transcriptional stress is mediated by ROS-induced R-loops
Autor: Ma, TS, a další
Vydáno: (2023)

APOBEC3B regulates R-loops and promotes transcription-associated mutagenesis in cancer
Autor: McCann, JL, a další
Vydáno: (2023)

The intrinsic ability of double-stranded DNA to carry out D-loop and R-loop formation
Autor: Takehiko Shibata, a další
Vydáno: (2020-01-01)

Mechanisms of transcriptional dysregulation in repeat expansion disorders.
Autor: Groh, M, a další
Vydáno: (2014)

Mechanisms underlining R-loop biology and implications for human disease
Autor: Junzhe Liu, a další
Vydáno: (2025-02-01)

Out of Balance
Autor: Douglas McCormick
Vydáno: (2008-03-01)

Senataxin: genome guardian at the interface of transcription and neurodegeneration
Autor: Groh, M, a další
Vydáno: (2016)

Transcription-dependent DNA double-strand breaks and human disease
Autor: Cristini, A, a další
Vydáno: (2020)

RNase H2, mutated in Aicardi‐Goutières syndrome, resolves co-transcriptional R-loops to prevent DNA breaks and inflammation
Autor: Cristini, A, a další
Vydáno: (2022)

Dual processing of R-loops and topoisomerase I induces transcription-dependent DNA double-strand breaks
Autor: Cristini, A, a další
Vydáno: (2019)

In And Out Of the Loop: External and Internal Modulation Of The Olivo-Cerebellar Loop
Autor: Avraham Manfred Libster, a další
Vydáno: (2013-04-01)

Looping out introns to help splicing.
Autor: Richard Robinson
Vydáno: (2006-02-01)

R-loopDB: a database for R-loop forming sequences (RLFS) and R-loops
Autor: Jenjaroenpun, Piroon, a další
Vydáno: (2017)

Transcription-dependent DNA double-strand breaks and human disease
Autor: Agnese Cristini, a další
Vydáno: (2020-03-01)

R-loop and diseases: the cell cycle matters
Autor: Yuqin Xu, a další
Vydáno: (2024-04-01)

Integrating out new fermions at one loop
Autor: Andrei Angelescu, a další
Vydáno: (2021-01-01)

Dual Processing of R-Loops and Topoisomerase I Induces Transcription-Dependent DNA Double-Strand Breaks
Autor: Agnese Cristini, a další
Vydáno: (2019-09-01)

AutoGAN: An Automated Human-Out-of-the-Loop Approach for Training Generative Adversarial Networks
Autor: Ehsan Nazari, a další
Vydáno: (2023-02-01)

RNase H2, mutated in Aicardi‐Goutières syndrome, resolves co-transcriptional R-loops to prevent DNA breaks and inflammation
Autor: Agnese Cristini, a další
Vydáno: (2022-05-01)

Autopilot, Mind Wandering, and the Out of the Loop Performance Problem
Autor: Jonas Gouraud, a další
Vydáno: (2017-10-01)

Effects of initial eye position on saccades evoked by microstimulation in the primate superior colliculus: implications for models of the SC read-out process
Autor: Jennifer M Groh, a další
Vydáno: (2011-01-01)

Human immunodeficiency virus-1 induces host genomic R-loops and preferentially integrates its genome near the R-loop regions
Autor: Kiwon Park, a další
Vydáno: (2024-12-01)

Comparison of Balance and Out of Balance Main Battle Tank Armaments
Autor: David J. Purdy
Vydáno: (2001-01-01)

Acid-Base Balance (Out of Print)
Autor: Alan Grogono
Vydáno: (2006-11-01)

Human 5' --> 3' exonuclease Xrn2 promotes transcription termination at co-transcriptional cleavage sites.
Autor: West, S, a další
Vydáno: (2004)

Hardware-In-the-Loop Equipment for the Development of an Automatic Perturbator for Clinical Evaluation of Human Balance Control
Autor: Carlo Ferraresi, a další
Vydáno: (2020-12-01)

Global balance and the environment - Development feedback loop
Autor: Mastrojen Grammenos
Vydáno: (2019-01-01)

R-loop landscape in mature human sperm: Regulatory and evolutionary implications
Autor: Maurice Scheuren, a další
Vydáno: (2023-04-01)

Hybrid Open-Loop Closed-Loop Control of Coupled Human–Robot Balance During Assisted Stance Transition With Extra Robotic Legs
Autor: Gonzalez, Daniel J., a další
Vydáno: (2020)

Reflexivity 3. Breaking out the Reflexive Loop to Decolonise Practice
Autor: Gail Simon
Vydáno: (2023-12-01)

Looping out loud: A multimodal analysis of humour on Vine
Autor: Vittorio Marone
Vydáno: (2017-01-01)

Natural products in a world out-of-balance
Autor: Geoffrey A. Cordell, a další
Vydáno: (2006-09-01)