Studies on the inhibition of human hypoxia inducible factor (HIF) hydroxylases
<p>Hypoxia inducible factor (HIF) is an α/β-heterodimeric transcription factor that regulates cellular responses to hypoxia in metazoans. The activity and stability of the HIF-α subunits are regulated by prolyl and asparaginyl hydroxylation. Human HIF-1α prolyl hydroxylation occurs at Pro402 a...
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| Diğer Yazarlar: | |
| Materyal Türü: | Tez |
| Dil: | English |
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2012
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