Improving SRM assay development: a global comparison between triple quadrupole, ion trap, and higher energy CID peptide fragmentation spectra.

In proteomics, selected reaction monitoring (SRM) is rapidly gaining importance for targeted protein quantification. The triple quadrupole mass analyzers used in SRM assays allow for levels of specificity and sensitivity hard to accomplish by more standard shotgun proteomics experiments. Often, an S...

全面介绍

书目详细资料
Main Authors: de Graaf, E, Altelaar, A, van Breukelen, B, Mohammed, S, Heck, A
格式: Journal article
语言:English
出版: 2011