PLU-1 is an H3K4 demethylase involved in transcriptional repression and breast cancer cell proliferation.

PLU-1 is an H3K4 demethylase involved in transcriptional repression and breast cancer cell proliferation.

Posttranslational modification of chromatin by histone methylation has wide-ranging effects on nuclear function, including transcriptional regulation, maintenance of genome integrity, and epigenetic inheritance. The enzymes utilized to place histone methylation marks are well characterized, but the...

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Huvudupphovsmän: Yamane, K, Tateishi, K, Klose, R, Fang, J, Fabrizio, L, Erdjument-Bromage, H, Taylor-Papadimitriou, J, Tempst, P, Zhang, Y
Materialtyp: Journal article
Språk:English
Publicerad: 2007

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