The enzymology of clavam and carbapenem biosynthesis.
The enzyme-catalysed reactions involved in formation of the bicyclic clavam and carbapenem nuclei, including beta-amino acid and beta-lactam formation, are discussed and compared with those involved in penicillin and cephalosporin biosynthesis. The common role of unusual oxidation reactions in the b...
Prif Awduron: | Kershaw, N, Caines, M, Sleeman, M, Schofield, C |
---|---|
Fformat: | Journal article |
Iaith: | English |
Cyhoeddwyd: |
2005
|
Eitemau Tebyg
-
Chemistry and biosynthesis of clavulanic acid and other clavams.
gan: Baggaley, K, et al.
Cyhoeddwyd: (1997) -
Reaction of clavams with elastase reveals a general method for inhibiting 'serine' enzymes
gan: Wilmouth, R, et al.
Cyhoeddwyd: (2000) -
Biosynthesis of carbapenem antibiotics: new carbapenam substrates for carbapenem synthase (CarC).
gan: Sleeman, M, et al.
Cyhoeddwyd: (2004) -
Enzymology of retinoic acid biosynthesis and degradation
gan: Natalia Y. Kedishvili
Cyhoeddwyd: (2013-07-01) -
Carboxymethylproline synthase (CarB), an unusual carbon-carbon bond-forming enzyme of the crotonase superfamily involved in carbapenem biosynthesis.
gan: Sleeman, M, et al.
Cyhoeddwyd: (2004)