High level transcription of the complement regulatory protein CD59 requires an enhancer located in intron 1.
CD59 is a complement regulatory protein and may also act as a signal-transducing molecule. CD59 transgenic mice have been generated using a CD59 minigene (CD59 minigene-1). Although this minigene contained a 4.6-kilobase pair 5'-flanking region from the human CD59 gene as a promoter, the expres...
Κύριοι συγγραφείς: | Tone, M, Diamond, L, Walsh, L, Tone, Y, Thompson, SA, Shanahan, E, Logan, J, Waldmann, H |
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Μορφή: | Journal article |
Γλώσσα: | English |
Έκδοση: |
1999
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Παρόμοια τεκμήρια
Παρόμοια τεκμήρια
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Transfection of human CD59 complementary DNA into rat cells confers resistance to human complement.
ανά: Walsh, L, κ.ά.
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The CD59 antigen--a multifunctional molecule.
ανά: Walsh, L, κ.ά.
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Cell- and tissue-specific expression of a human CD59 minigene in transgenic mice.
ανά: Diamond, L, κ.ά.
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Structure and chromosomal location of mouse and human CD52 genes.
ανά: Tone, M, κ.ά.
Έκδοση: (1999) -
Gene structure of human CD59 and demonstration that discrete mRNAs are generated by alternative polyadenylation.
ανά: Tone, M, κ.ά.
Έκδοση: (1992)