Human and simian immunodeficiency viruses: virus-receptor interactions.
The major cellular receptor for the primate immunodeficiency viruses is the CD4 molecule. As well as mediating virion attachment to the cell surface, CD4 is thought to activate the viral fusion pathway. CD4 is not, however, sufficient for viral entry; other molecules are probably involved, and in ce...
| Main Authors: | , , , |
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| Format: | Journal article |
| Language: | English |
| Published: |
1993
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| _version_ | 1826264542432198656 |
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| author | Signoret, N Poignard, P Blanc, D Sattentau, Q |
| author_facet | Signoret, N Poignard, P Blanc, D Sattentau, Q |
| author_sort | Signoret, N |
| collection | OXFORD |
| description | The major cellular receptor for the primate immunodeficiency viruses is the CD4 molecule. As well as mediating virion attachment to the cell surface, CD4 is thought to activate the viral fusion pathway. CD4 is not, however, sufficient for viral entry; other molecules are probably involved, and in certain circumstances these may substitute for CD4. Viral tropism and cytopathogenicity are also influenced by receptor interactions. |
| first_indexed | 2024-03-06T20:09:29Z |
| format | Journal article |
| id | oxford-uuid:2a1486a6-9619-4b69-854b-b9534a89e76d |
| institution | University of Oxford |
| language | English |
| last_indexed | 2024-03-06T20:09:29Z |
| publishDate | 1993 |
| record_format | dspace |
| spelling | oxford-uuid:2a1486a6-9619-4b69-854b-b9534a89e76d2022-03-26T12:22:54ZHuman and simian immunodeficiency viruses: virus-receptor interactions.Journal articlehttp://purl.org/coar/resource_type/c_dcae04bcuuid:2a1486a6-9619-4b69-854b-b9534a89e76dEnglishSymplectic Elements at Oxford1993Signoret, NPoignard, PBlanc, DSattentau, QThe major cellular receptor for the primate immunodeficiency viruses is the CD4 molecule. As well as mediating virion attachment to the cell surface, CD4 is thought to activate the viral fusion pathway. CD4 is not, however, sufficient for viral entry; other molecules are probably involved, and in certain circumstances these may substitute for CD4. Viral tropism and cytopathogenicity are also influenced by receptor interactions. |
| spellingShingle | Signoret, N Poignard, P Blanc, D Sattentau, Q Human and simian immunodeficiency viruses: virus-receptor interactions. |
| title | Human and simian immunodeficiency viruses: virus-receptor interactions. |
| title_full | Human and simian immunodeficiency viruses: virus-receptor interactions. |
| title_fullStr | Human and simian immunodeficiency viruses: virus-receptor interactions. |
| title_full_unstemmed | Human and simian immunodeficiency viruses: virus-receptor interactions. |
| title_short | Human and simian immunodeficiency viruses: virus-receptor interactions. |
| title_sort | human and simian immunodeficiency viruses virus receptor interactions |
| work_keys_str_mv | AT signoretn humanandsimianimmunodeficiencyvirusesvirusreceptorinteractions AT poignardp humanandsimianimmunodeficiencyvirusesvirusreceptorinteractions AT blancd humanandsimianimmunodeficiencyvirusesvirusreceptorinteractions AT sattentauq humanandsimianimmunodeficiencyvirusesvirusreceptorinteractions |