Neonatal diabetes - The role of KCNJ11 (Kir6.2)

Neonatal diabetes - The role of KCNJ11 (Kir6.2)

ATP-sensitive potassium (KATP) channels are inhibited by intracellular ATP and activated by MgADP. As a consequence, they couple the metabolic state of the cell to its electrical activity. In pancreatic β-cells KATP channels regulate glucose-dependent insulin secretion and are the target for sulphon...

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Autor Principal:	Tammaro, P
Formato:	Journal article
Idioma:	English
Publicado:	2007

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