Development of an in vitro assay and demonstration of Plasmodium berghei liver-stage inhibition by TRAP-specific CD8+ T cells

Development of an in vitro assay and demonstration of Plasmodium berghei liver-stage inhibition by TRAP-specific CD8+ T cells

The development of an efficacious vaccine against the Plasmodium parasite remains a top priority. Previous research has demonstrated the ability of a prime-boost virally vectored sub-unit vaccination regimen, delivering the liver-stage expressed malaria antigen TRAP, to produce high levels of antige...

Полное описание

Библиографические подробности
Главные авторы:	Longley, R, Bauza, K, Ewer, K, Hill, A, Spencer, A
Формат:	Journal article
Язык:	English
Опубликовано:	Public Library of Science 2015

Схожие документы

Development of an in vitro assay and demonstration of Plasmodium berghei liver-stage inhibition by TRAP-specific CD8+ T cells.
по: Rhea J Longley, и др.
Опубликовано: (2015-01-01)

An in vitro T cell killing assay to assess new Plasmodium falciparum vaccine candidates
по: Longley, R, и др.
Опубликовано: (2013)

Malaria vaccines: identifying Plasmodium falciparum liver-stage targets
по: Longley, R, и др.
Опубликовано: (2015)

The importance of the immunodominant CD8+ T cell epitope of Plasmodium berghei circumsporozoite protein in parasite- and vaccine-induced protection
по: Gibbins, MP, и др.
Опубликовано: (2020)

Immunization with radiation-attenuated Plasmodium berghei sporozoites induces liver cCD8alpha+DC that activate CD8+T cells against liver-stage malaria.
по: Ousman Jobe, и др.
Опубликовано: (2009-01-01)

Infectious Sporozoites of Plasmodium berghei Effectively Activate Liver CD8α+ Dendritic Cells
по: Rajesh Parmar, и др.
Опубликовано: (2018-02-01)

An in vitro assay to measure antibody-mediated inhibition of P. berghei sporozoite invasion against P. falciparum antigens
по: Rodriguez-Galan, A, и др.
Опубликовано: (2017)

A role for CD4+ and CD8+ cells and not for CD25+ cells in the control of Plasmodium berghei Anka blood stage parasites in rats
по: Acroute Dit Vampouille A., и др.
Опубликовано: (2010-03-01)

Protection from liver-stage malaria is dependent on a fine balance between the number of infected hepatocytes and effector CD8(+) T-cells
по: Spencer, A, и др.
Опубликовано: (2014)

CD8+ T effector memory cells protect against liver-stage malaria.
по: Reyes-Sandoval, A, и др.
Опубликовано: (2011)

CD8+ T effector memory cells protect against liver-stage malaria
по: Reyes-Sandoval, A, и др.
Опубликовано: (2011)

The threshold of protection from liver-stage malaria relies on a fine balance between the number of infected hepatocytes and effector CD8+ T cells present in the liver
по: Spencer, A, и др.
Опубликовано: (2017)

Plasmodium berghei liver stage parasites exploit host GABARAP proteins for TFEB activation
по: Jacqueline Schmuckli-Maurer, и др.
Опубликовано: (2024-11-01)

Association of Plasmodium berghei With the Apical Domain of Hepatocytes Is Necessary for the Parasite's Liver Stage Development
по: Lakshmi Balasubramanian, и др.
Опубликовано: (2020-01-01)

Intravital observation of Plasmodium berghei sporozoite infection of the liver.
по: Ute Frevert, и др.
Опубликовано: (2005-06-01)

Identification of targets of CD8⁺ T cell responses to malaria liver stages by genome-wide epitope profiling.
по: Hafalla, J, и др.
Опубликовано: (2013)

Identification of immunodominant responses to the Plasmodium falciparum antigens PfUIS3, PfLSA1 and PfLSAP2 in multiple strains of mice
по: Longley, R, и др.
Опубликовано: (2015)

Impact of Galectin-Receptor Interactions on Liver Pathology During the Erythrocytic Stage of Plasmodium berghei Malaria
по: Yifan Wu, и др.
Опубликовано: (2021-11-01)

Effects of Artemisin and Moringa oleifera Extract Combination on CD4+ and CD8+ Percentage of Mice Infected with Plasmodium berghei
по: Melda Fio Flora BR. Sijabat, и др.
Опубликовано: (2016-11-01)

Early Activation of Lung CD8+ T Cells After Immunization with Live Plasmodium berghei Malaria Sporozoites
по: Roos van Schuijlenburg, и др.
Опубликовано: (2025-03-01)

A novel genetic technique in Plasmodium berghei allows liver stage analysis of genes required for mosquito stage development and demonstrates that de novo heme synthesis is essential for liver stage development in the malaria parasite.
по: Upeksha L Rathnapala, и др.
Опубликовано: (2017-06-01)

The utility of Plasmodium berghei as a rodent model for anti-merozoite malaria vaccine assessment
по: Goodman, A, и др.
Опубликовано: (2013)

Comparative assessment of vaccine vectors encoding ten malaria antigens identifies two protective liver-stage candidates.
по: Longley, R, и др.
Опубликовано: (2015)

Interaction between host complement and mosquito-midgut-stage Plasmodium berghei.
по: Margos, G, и др.
Опубликовано: (2001)

Plasmodium berghei MAPK1 displays differential and dynamic subcellular localizations during liver stage development.
по: Jannika Katharina Wierk, и др.
Опубликовано: (2013-01-01)

Maintenance of the Plasmodium berghei life cycle.
по: Sinden, R, и др.
Опубликовано: (2002)

Efficacy of a Plasmodium vivax malaria vaccine using ChAd63 and modified vaccinia Ankara expressing thrombospondin-related anonymous protein as assessed with transgenic Plasmodium berghei parasites.
по: Bauza, K, и др.
Опубликовано: (2014)

Screening the Global Health Priority Box against Plasmodium berghei liver stage parasites using an inexpensive luciferase detection protocol
по: Gia-Bao Nguyen, и др.
Опубликовано: (2024-11-01)

Differential induction of malaria liver pathology in mice infected with Plasmodium chabaudi AS or Plasmodium berghei NK65
по: Diletta Scaccabarozzi, и др.
Опубликовано: (2018-01-01)

Late killing of Plasmodium berghei sporozoites in the liver by an anti-circumsporozoite protein antibody
по: Manuela C Aguirre-Botero, и др.
Опубликовано: (2025-02-01)

Mitochondrial peroxidase TPx-2 is not essential in the blood and insect stages of <it>Plasmodium berghei</it>
по: Masuda-Suganuma Hirono, и др.
Опубликовано: (2012-11-01)

Suppressive effect of azithromycin on <it>Plasmodium berghei </it>mosquito stage development and apicoplast replication
по: Tanaka Yoshiya, и др.
Опубликовано: (2010-03-01)

Progression of Plasmodium berghei through Anopheles stephensi is density-dependent.
по: Sinden, R, и др.
Опубликовано: (2007)

Progression of Plasmodium berghei through Anopheles stephensi is density-dependent
по: Sinden, R, и др.
Опубликовано: (2007)

Assessment of the Plasmodium falciparum pre-erythrocytic antigen UIS3 as a potential candidate for a malaria vaccine
по: Longley, R, и др.
Опубликовано: (2016)

Characterisation and expression of pbs25, a sexual and sporogonic stage specific protein of Plasmodium berghei.
по: del Carmen Rodriguez, M, и др.
Опубликовано: (2000)

Single-cell quantitative bioimaging of P. berghei liver stage translation
по: James L. McLellan, и др.
Опубликовано: (2023-12-01)

Progression of Plasmodium berghei through Anopheles stephensi is density-dependent.
по: Robert E Sinden, и др.
Опубликовано: (2007-12-01)

Invariant Valpha14 chain NKT cells promote Plasmodium berghei circumsporozoite protein-specific gamma interferon- and tumor necrosis factor alpha-producing CD8+ T cells in the liver after poxvirus vaccination of mice.
по: Korten, S, и др.
Опубликовано: (2005)

Neddylation is essential for malaria transmission in Plasmodium berghei
по: Bandita Nayak, и др.
Опубликовано: (2024-04-01)