Expression of the bcl-2 oncogene product and chromosomal translocation t(14;18) in Hodgkin's disease.

Expression of the bcl-2 oncogene product and chromosomal translocation t(14;18) in Hodgkin's disease.

The B-cell lymphoma/leukemia oncogene bcl-2 takes part in crucial regulatory events in B-cell maturation and differentiation. The reciprocal chromosomal translocation t(14;18), leading to overexpression of this oncogene, can be found in the majority of follicular lymphomas and much less frequently i...

Podrobná bibliografie
Hlavní autoři:	Lorenzen, J, Hansmann, M, Pezzella, F, Hesse, C, Kneba, M, Gatter, K, Fischer, R
Médium:	Journal article
Jazyk:	English
Vydáno:	1992

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