Expression of the bcl-2 oncogene product and chromosomal translocation t(14;18) in Hodgkin's disease.
The B-cell lymphoma/leukemia oncogene bcl-2 takes part in crucial regulatory events in B-cell maturation and differentiation. The reciprocal chromosomal translocation t(14;18), leading to overexpression of this oncogene, can be found in the majority of follicular lymphomas and much less frequently i...
主要な著者: | , , , , , , |
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フォーマット: | Journal article |
言語: | English |
出版事項: |
1992
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