Elevated circulating amyloid concentrations in obesity and diabetes promote vascular dysfunction.

Elevated circulating amyloid concentrations in obesity and diabetes promote vascular dysfunction.

Diabetes, obesity and Alzheimer’s disease (AD) are associated with vascular complications and impaired nitric oxide (NO) production. Furthermore, increased β-site amyloid precursor protein (APP)-cleaving enzyme 1 (BACE1), APP and β-amyloid (Aβ) are linked with vascular disease development and raised...

書誌詳細
主要な著者:	Meakin, PJ, Coull, BM, Tuharska, Z, McCaffery, C, Akoumianakis, I, Antoniades, C, Brown, J, Griffin, KJ, Platt, F, Ozber, CH, Yuldasheva, NY, Makava, N, Skromna, A, Prescott, AR, McNeilly, AD, Siddiqui, MK, Palmer, CNA, Khan, F, Ashford, MLJ
フォーマット:	Journal article
言語:	English
出版事項:	American Society for Clinical Investigation 2020

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