Synthetic tools for studying the chemical biology of InsP8

Synthetic tools for studying the chemical biology of InsP8

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To synthesise stabilised mimics of InsP8, the most phosphorylated inositol phosphate signalling molecule in Nature, we replaced its two diphosphate (PP) groups with either phosphonoacetate (PA) or methylenebisphosphonate (PCP) groups. Utility of the PA and PCP analogues was verified by structural an...

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Detalhes bibliográficos
Main Authors:	Riley, A, Wang, H, Shears, S, Potter, BVL
Formato:	Journal article
Idioma:	English
Publicado em:	Royal Society of Chemistry 2015

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