Synthetic tools for studying the chemical biology of InsP8

To synthesise stabilised mimics of InsP8, the most phosphorylated inositol phosphate signalling molecule in Nature, we replaced its two diphosphate (PP) groups with either phosphonoacetate (PA) or methylenebisphosphonate (PCP) groups. Utility of the PA and PCP analogues was verified by structural an...

Disgrifiad llawn

Manylion Llyfryddiaeth
Prif Awduron: Riley, A, Wang, H, Shears, S, Potter, BVL
Fformat: Journal article
Iaith:English
Cyhoeddwyd: Royal Society of Chemistry 2015