Nucleobase recognition in ssDNA at the central constriction of the alpha-hemolysin pore.

Nanopores are under investigation for single-molecule DNA sequencing. The alpha-hemolysin (alphaHL) protein nanopore contains three recognition points capable of nucleobase discrimination in individual immobilized ssDNA molecules. We have modified the recognition point R(1) by extensive mutagenesis...

詳細記述

書誌詳細
主要な著者: Stoddart, D, Heron, A, Klingelhoefer, J, Mikhailova, E, Maglia, G, Bayley, H
フォーマット: Journal article
言語:English
出版事項: 2010