Modification of K-ATP channels in pancreatic beta-cells by trypsin.

Modification of K-ATP channels in pancreatic beta-cells by trypsin.

The inside-out configuration of the patch-clamp method was used to study the effects of trypsin on the activity of ATP-sensitive potassium (K-ATP) channels from isolated mouse pancreatic beta-cells. Trypsin (20 micrograms/ml) irreversibly enhanced channel activity around twofold by reducing the inte...

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Dades bibliogràfiques
Autors principals:	Proks, P, Ashcroft, F
Format:	Journal article
Idioma:	English
Publicat:	1993

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