Pyruvate enolate arylation and alkylation: OBO ester protected pyruvates as useful reagents in organic synthesis

Pyruvate enolate arylation and alkylation: OBO ester protected pyruvates as useful reagents in organic synthesis

A protected pyruvate equivalent is described that allows arylation and arylation/alkylation reactions to be performed at the methyl group. Utilization of the OBO derivative of the pyruvate ester allowed the application of palladium catalyzed arylation reactions together with subsequent alkylation, u...

Полное описание

Библиографические подробности
Главные авторы:	Alves Esteves, C, Hall, C, Smith, P, Donohoe, T
Формат:	Journal article
Язык:	English
Опубликовано:	American Chemical Society 2017

Схожие документы

OBO-protected pyruvates as reagents for the synthesis of functionalized heteroaromatic compounds
по: Alves Estaves, C, и др.
Опубликовано: (2018)

Catalytic enolate arylation with 3-bromoindoles allows the formation of β-carbolines.
по: Alves Esteves, C, и др.
Опубликовано: (2017)

Expedient synthesis of substituted aromatics via the alpha-arylation of enolates
по: Pilgrim, B, и др.
Опубликовано: (2013)

Palladium-catalysed enolate arylation in the synthesis of aromatic heterocycles and substituted heterocycles
по: Esteves, C
Опубликовано: (2017)

Modular isoquinoline synthesis using catalytic enolate arylation and in situ functionalization.
по: Pilgrim, B, и др.
Опубликовано: (2013)

Characterization of bacterial-type phospho<it>enol</it>pyruvate carboxylase expressed in male gametophyte of higher plants
по: Igawa Tomoko, и др.
Опубликовано: (2010-09-01)

Palladium-catalyzed enolate arylation as a key C-C bond-forming reaction for the synthesis of isoquinolines.
по: Pilgrim, B, и др.
Опубликовано: (2015)

Palladium-catalysed enolate arylation in the synthesis of isoquinolines
по: Gatland, A, и др.
Опубликовано: (2014)

Copper-catalyzed arylation of alkyl halides with arylaluminum reagents
по: Bijay Shrestha, и др.
Опубликовано: (2015-12-01)

Expedient Synthesis of Alkyl and Aryl Thioethers Using Xanthates as Thiol-Free Reagents
по: Jinli Nie, и др.
Опубликовано: (2024-05-01)

The Multifaceted Pyruvate Metabolism: Role of the Mitochondrial Pyruvate Carrier
по: Joséphine Zangari, и др.
Опубликовано: (2020-07-01)

Gold-catalyzed alkylation of silyl enol ethers with ortho-alkynylbenzoic acid esters
по: Haruo Aikawa, и др.
Опубликовано: (2011-05-01)

Genetic and Pharmacological Inhibition of Autophagy Increases the Monoubiquitination of Non-Photosynthetic Phospho<i>enol</i>pyruvate Carboxylase
по: Guillermo Baena, и др.
Опубликовано: (2020-12-01)

The Allylic Alkylation of Ketone Enolates
по: Dr. Lukas Junk, и др.
Опубликовано: (2020-09-01)

On the origins of diastereoselectivity in the alkylation of diketopiperazine enolates
по: Bull, S, и др.
Опубликовано: (2007)

Palladium-catalysed intramolecular enolate O-arylation and thio-enolate S-arylation: synthesis of benzo[b]furans and benzo[b]thiophenes
по: Willis, M, и др.
Опубликовано: (2006)

Inhibition of pyruvate dehydrogenase kinase by pyruvate in cultured cardiac myocytes
по: Priestman, D, и др.
Опубликовано: (1997)

Studies on a maize rubisco null mutant and the C-4 phospho enol pyruvate carboxylase (PEPC) light-signal transduction chain.
по: Smith, L, и др.
Опубликовано: (1997)

Overexpression of an <i>Agave</i> Phospho<i>enol</i>pyruvate Carboxylase Improves Plant Growth and Stress Tolerance
по: Degao Liu, и др.
Опубликовано: (2021-03-01)

Model-guided metabolic rewiring to bypass pyruvate oxidation for pyruvate derivative synthesis by minimizing carbon loss
по: Yun Zhang, и др.
Опубликовано: (2024-03-01)

Oxazinanones as chiral auxiliaries: synthesis and evaluation in enolate alkylations and aldol reactions.
по: Davies, S, и др.
Опубликовано: (2006)

SYNTHESIS AND STRUCTURAL STUDIES ON FOURAND SIX-COORDINATED COMPLEXES OF (BUTYL/ETHYL)PHENYLTIN DICHLORIDES WITH ALKYL PYRUVATE AROYLHYDRAZONES
по: Sonika,, и др.
Опубликовано: (1995-08-01)

Alkylation of Ethyl Pyruvate via Reductive Coupling of Alkenes and Ethyl 2-(Benzenesulfonylamino)acrylate
по: Vincent Darmency, и др.
Опубликовано: (2005-03-01)

Short and Efficient Syntheses of Protoberberine Alkaloids using Palladium-Catalyzed Enolate Arylation.
по: Gatland, A, и др.
Опубликовано: (2014)

Effect and Regulation of Pyruvate on Bacillomycin D Synthesis
по: Wenjie MA, и др.
Опубликовано: (2022-11-01)

Molecular Cloning of Novel-Type Phospho<i>enol</i>pyruvate Carboxylase Isoforms in Pitaya (<i>Hylocereus undatus</i>)
по: Keiichi Nomura, и др.
Опубликовано: (2020-09-01)

Pyruvate kinase deficiency
по: Alberto Zanella, и др.
Опубликовано: (2007-06-01)

Prokaryotic Expression of Phospho<i>enol</i>pyruvate Carboxylase Fragments from Peanut and Analysis of Osmotic Stress Tolerance of Recombinant Strains
по: Jiaqi Tu, и др.
Опубликовано: (2021-02-01)

Berberine Reduces Pyruvate-driven Hepatic Glucose Production by Limiting Mitochondrial Import of Pyruvate through Mitochondrial Pyruvate Carrier 1Research in Context
по: Aiyun Li, и др.
Опубликовано: (2018-08-01)

Pyruvate kinase deficiency protects against malaria in humans
по: Pierre M. Durand, и др.
Опубликовано: (2008-06-01)

Enhanced pyruvate metabolism in plastids by overexpression of putative plastidial pyruvate transporter in Phaeodactylum tricornutum
по: Seungbeom Seo, и др.
Опубликовано: (2020-07-01)

Palladium catalysed aryl enol ether synthesis from vinyl triflates.
по: Willis, M, и др.
Опубликовано: (2003)

Synthesis of MAPA Reagents and 2-Alkyl(aryl)aminopyridines from 2-Bromopyridine Using the Goldberg Reaction
по: Daniel L. Comins
Опубликовано: (2022-03-01)

Dichloroacetate and Pyruvate Metabolism: Pyruvate Dehydrogenase Kinases as Targets Worth Investigating for Effective Therapy of Toxoplasmosis
по: Mariana Galvão Ferrarini, и др.
Опубликовано: (2021-02-01)

Enantiopure bicyclic piperidinones: stereoselectivity in lactam enolate alkylations.
по: Brewster, A, и др.
Опубликовано: (2004)

Structural studies on pyruvate kinase
по: Fell, D
Опубликовано: (1974)

Genome-Wide In Silico Analysis and Expression Profiling of Phospho<i>enol</i>pyruvate Carboxylase Genes in Loquat, Apple, Peach, Strawberry and Pear
по: Cao Zhi, и др.
Опубликовано: (2021-12-01)

Recent Advances in Metabolic Engineering for the Biosynthesis of Phosphoenol Pyruvate–Oxaloacetate–Pyruvate-Derived Amino Acids
по: Lianghong Yin, и др.
Опубликовано: (2024-06-01)

Pyruvic Acid Production from Sucrose by <i>Escherichia coli</i> Pyruvate Dehydrogenase Variants
по: W. Chris Moxley, и др.
Опубликовано: (2023-05-01)

Role of the Pyruvate Dehydrogenase Complex in Metabolic Remodeling: Differential Pyruvate Dehydrogenase Complex Functions in Metabolism
по: Sungmi Park, и др.
Опубликовано: (2018-08-01)