Syntheses of (6S)-cephalosporins from 6-aminopenicillanic acid

Syntheses of (6S)-cephalosporins from 6-aminopenicillanic acid

Two practical routes to (6S,7S)-cephalosporins from 6-aminopenicillanic acid (6-APA) are described. In the first, 6-APA was converted to (2S,4S,5S,6S)-penicillin sulfoxide 49, which underwent Morin ring expansion to a protected (6S,7S)-cephem 50. In the second, ester 15 was converted to (2S,4S,5S,6R...

Disgrifiad llawn

Manylion Llyfryddiaeth
Prif Awduron:	Fekner, T, Baldwin, J, Adlington, R, Jones, T, Prout, C, Schofield, C
Fformat:	Journal article
Iaith:	English
Cyhoeddwyd:	2000

Eitemau Tebyg

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