Novel and selective small molecule inhibitors and activators for the prolyl hydroxylase domain enzyme
<p>Hypoxia Inducible Factors (HIF) functions are master regulators of oxygen homeostasis and have a key role in the physiological responses to hypoxia including angiogenesis and erythropoiesis. Under hypoxia, levels of HIF-α subunits increase, they hetereodimerise with HIF-1β sub unit and pr...
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| フォーマット: | 学位論文 |
| 出版事項: |
2018
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