Route of monocyte differentiation determines their cytokine production profile: CD40 ligation induces interleukin 10 expression.
Interleukin 10 is a potent anti-inflammatory and immunomodulatory cytokine. Little is known regarding its induction in monocytes/macrophages, however LPS, a reproducible trigger of IL-10, is augmented by direct contact with T cells. In this context, the role of CD40-ligation is investigated. In the...
मुख्य लेखकों: | Foey, A, Feldmann, M, Brennan, F |
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स्वरूप: | Journal article |
भाषा: | English |
प्रकाशित: |
2000
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समान संसाधन
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CD40 ligation induces macrophage IL-10 and TNF-alpha production: differential use of the PI3K and p42/44 MAPK-pathways.
द्वारा: Foey, A, और अन्य
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Cytokine stimulation of T lymphocytes regulates their capacity to induce monocyte production of tumor necrosis factor-alpha, but not interleukin-10: possible relevance to pathophysiology of rheumatoid arthritis.
द्वारा: Sebbag, M, और अन्य
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The importance of T cell interactions with macrophages in rheumatoid cytokine production.
द्वारा: Brennan, F, और अन्य
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Two inhibitors of pro-inflammatory cytokine release, interleukin-10 and interleukin-4, have contrasting effects on release of soluble p75 tumor necrosis factor receptor by cultured monocytes.
द्वारा: Joyce, D, और अन्य
प्रकाशित: (1994) -
Regulation of monocyte IL-10 synthesis by endogenous IL-1 and TNF-alpha: role of the p38 and p42/44 mitogen-activated protein kinases.
द्वारा: Foey, A, और अन्य
प्रकाशित: (1998)