Altered TCR signaling from geometrically repatterned immunological synapses.
The immunological synapse is a specialized cell-cell junction that is defined by large-scale spatial patterns of receptors and signaling molecules yet remains largely enigmatic in terms of formation and function. We used supported bilayer membranes and nanometer-scale structures fabricated onto the...
Main Authors: | , , , |
---|---|
Format: | Journal article |
Language: | English |
Published: |
2005
|