Altered TCR signaling from geometrically repatterned immunological synapses.

The immunological synapse is a specialized cell-cell junction that is defined by large-scale spatial patterns of receptors and signaling molecules yet remains largely enigmatic in terms of formation and function. We used supported bilayer membranes and nanometer-scale structures fabricated onto the...

Full description

Bibliographic Details
Main Authors: Mossman, K, Campi, G, Groves, J, Dustin, M
Format: Journal article
Language:English
Published: 2005